About Public Health

boy running through sprinkler

The mission of the IR-4 Project is to facilitate registration of sustainable pest management technology for specialty crops and minor uses. IR-4 assists registration of public health pesticides as a minor use.

From 2008 to 2017, the IR-4 Public Health Pesticide Program expanded the mission of IR-4 to include the facilitation of the development and registration of new public health pesticides to protect the public from insects and other arthropods that transmit human diseases.

The PHP Program was created to help fill and maintain the toolbox of toxicants, repellents, attractants, and other chemical tools used to manage mosquitoes, ticks, sand flies, and other arthropods that transmit human or animal disease. Major partners included the US Department of Defense’s Deployed War-fighter Protection Program and the USDA-ARS.

A particular priority was ensuring that deployed military personnel are protected from arthropods that carry human disease and that the chemical tools used for this purpose have been completely screened for safety and efficacy.

The IR-4 PHP’s Program also addressed:

  • improved integration of chemical tools into broad Integrated Vector Management (IVM) strategies
  • support for the regulatory needs of existing PHP’s
  • development of standard data dossiers and other methods to improve the PHP regulatory process, and
  • research and outreach.

Regulatory Support

The IR-4 PHP Program focused on supporting new chemical tools through the regulatory review process, which ensures their safety, both in terms of human health and environmental protection. These new tools included active ingredients. new product types, and newly formulated end-use products. IR-4 support included regulatory assistance and limited in-house or contracted data collection. This public assistance was needed because availability of PHP products has been recognized as a public interest, but the small market that exists for public health pesticides does not always provide the financial incentives needed for private industry to undertake this work alone.


This database currently contains information on approximately 1000 materials that are significant to the control of arthropods that can transmit infectious organisms to humans and/or domestic animals. Most of the materials are compounds or mixtures that serve as insect toxicants, repellents, or attractants. Some are specific isomers or forms of materials that are usually manufactured and sold as mixtures. Others are synergists, adjuvents, or carriers. A few are pesticide metabolites (break-down products). The list does not yet include specific formulated end-use products, although we plan to add this feature later this year. For now, product names can be used to help identify key constituent materials.

To search for a particular material, either type in a segment of a name or identifying number in the “Keyword Search” box and hit “submit”; or scroll through the list of Identifiers, select one or more, and hit “submit”. There are about 5,000 identifiers in the list, including chemical names, common names, trade names, and identifying numbers (CAS, EPA, etc.), as many materials have multiple identifiers. The list of identifiers is not complete, and, in particular, is missing many trade names at this time.

To search for materials with a specific EPA registration status, click on a registration category under “EPA Registration” and hit “submit.” To search for materials with active product registrations for a particular pest, click on the registration status under the pest and hit “submit.”
Disclaimer: All information provided in this database was collected from public data sites, and no proprietary data was included. Data in this site are compiled and presented, but were not generated, by IR-4, and their accuracy cannot be guaranteed. All references to specific products, or references to other data sources, are informational only, and do not constitute an endorsement by IR-4 or any affiliated institution.

Former Program Contacts

Program Manager:
Karl Malamud-Roam, PhD