BAS 440i (afidopyropen) is a new insecticide being developed by BASF for the control of piercing and sucking insect pests such as aphids, whiteflies, psyllids, scales and leafhoppers. The IR-4 Project completed 106 crop safety trials on 42 environmental horticulture plant species or genera from 2015 through 2019. In these trials, 24 genera or species exhibited minimal or no injury after foliar applications in a minimum of 3 trials for each crop; these can be added to a list of tolerant plants in the new label for this active ingredient. All trials for 18 other species or genera exhibited minimal or no injury in the limited number of trials (one or two) for each crop with the exception of dahlia which had moderate injury in one trial.