Fuerte (flumioxazin + prodiamine) has been registered in the United States since 2018. Starting in 2020, the IR-4 Project has been screening additional crops for their tolerance to over the top applications. During 2018 to 2021, 31 crop safety trials on 20 environmental horticulture plant species or genera. In general, Fuerte exhibited no or minimal negative impact in these trials. Two plant species or genera fell into this category as did 13 additional crops so far with just 1 or 2 trials completed. For two crop species, there was no or little injury exhibited at the 1X or 2X rates, but significant phytotoxicity occurred at 4X.