Pydiflumetofen is a new fungicide being developed by Syngenta for the control of leaf spots (Septoria, Cercospora, Alternaria, Venturia), powdery mildew, Fusarium, Botrytis, Sclerotinia, Corynespora, and other foliar diseases. The IR-4 Project completed 61 crop safety trials on 22 ornamental horticulture plant species or genera during 2015 to 2019. In these trials, all 22 species or genera exhibited minimal or no injury. Ten genera exhibited minimal or no injury in 3 trials and 12 species or genera exhibited minimal or no injury in the limited number of trials (one or two) for each crop. Syngenta may consider adding these to the label.