Flutianil is a new fungicide being developed by Nichino for the control of powdery mildew on environmental horticulture crops. The IR-4 Project completed 21 crop safety trials on 12 environmental horticulture plant species or genera during 2018 to 2021. In these trials, 12 species or genera exhibited minimal or no injury. Three species or genera (Gerbera jamesonii, Hydrangea macrophylla, Rosa sp) exhibited minimal or no injury in 3 trials and 9 species or genera exhibited minimal or no injury in the limited number of trials (one or two) for each crop. When first registered, it may be possible to include these in the list of crops with no known adverse impact.